Faculty members from the Construction Engineering and Management program are part of a local industry-academia collaborative team that has been awarded a nearly $3 million grant by the Colorado Department of Transportation (CDOT). The grant, entitled, “Project Management Employee Development Program (PMEDP)” was given notice to proceed this month and will support a three-year project that seeks to “enhance CDOT’s project management techniques, practices, and applications through a comprehensive blended and integrated employee development program in order to reinforce a culture of project management within CDOT.”
CU Denver is partnering with LS Gallegos & Associates Inc. and AECOM on the project. The CEM program is excited to serve as the lead on one of the largest program elements, Training Course Implementation. The CEM program is confident such work, as highlighted in the proposal, will solidify the fact that “In the past CDOT has had a close working relationship with CU Denver. This program will provide the opportunity to continue that relationship to the benefit of CDOT and CU Denver.”
Richard Benninger, Assistant Professor in the Department of Bioengineering, has been awarded two NIH Research Project (R01) grants from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). These two grants are to the amount of $1,749,375 and $1,749,375 in total costs, each over 5 years. Each research project grant focuses on studying the islets of Langerhans and their dysfunction in different forms of diabetes. Diabetes, a disease that afflicts close to 400M people world-wide, is characterized by a loss of glucose homeostasis which can lead to many diabetic complications including blindness, kidney disease, cardiovascular disease and limb amputations. Almost all cases of diabetes results from dysfunction to the insulin secreting beta cells in the islets of Langerhans, leading to insufficient secretion of the hormone insulin which regulates blood glucose homeostasis. Most treatments for diabetes therefore aim to prevent, restore or replace the disrupted secretion of insulin.
The first R01-funded project entitled “Emergent multi-cellular properties regulating pancreatic islet function” will apply quantitative fluorescence microscopy approaches, optogenetics and computational modelling to examine the cell signaling dynamics underlying insulin secretion from the islets of Langerhans. Specifically this project will focus on characterizing functional sub-populations of beta cells and determining how specific subpopulations of cells can exert disproportionate control over multiple functions of the islet through coupled dynamic processes; in healthy conditions and diabetic conditions caused by single gene mutations.
The second R01-funded project entitled “Multicellular interactions and dynamics of pancreatic islet function in diabetes” will examine dysfunction to the islets of Langerhans and regulation of insulin secretion during the progression of type2 diabetes. Specifically this project will focus on the important role of gap junction channels which mediate electrical communication between insulin-secreting beta cells. This includes characterizing the role of gap junction channel disruption in islet dysfunction during the progression of type2 diabetes, and determining ways gap junction coupling can be modulated to prevent the decline in beta cell mass and recover glucose-stimulated insulin secretion.
Together these projects will examine different ways that the function of the islets of Langerhans are disrupted in diabetes and discover strategies in which islet function can be restored; towards developing new treatments for different forms of diabetes.
The fourth annual College of Engineering and Applied Science Year-End Celebration took place on Friday, May 15, at Ninth Street Park on the Auraria Campus. Nearly 200 people from the college community attended the event and enjoyed delicious food, a photobooth, badminton, a visit from Milo the Lynx, and a lively awards ceremony. Check out the slideshow below, and mark your calendars for May 13, 2016 for next year’s Celebration.
Daewon Park, assistant professor of bioengineering, received an R21 grant from the National Eye Institute with his research titled “A Functional Reverse Thermal Gel for Retinal Ganglion Cell Axon Regeneration.” With this grant, Dr. Park will develop a bioinspired neurotrophic factor-releasing system for the regeneration of damaged retinal ganglion cell axon. This research will provide a platform of material-based treatment methodology of neural protection and regeneration.
Bioengineering undergraduate student, Adam Rauff was awarded a 2015-2016 Undergraduate Research Opportunity Program (UROP) grant. Adam will be working with Dana Carpenter, Assistant Professor in the Department of Mechanical Engineering, on a project titled, “Investigating the Effects of Weight-Bearing Function on Bone Microstructure.” The research delves into the function of osteocytes (mature bone cells) and their mechanosensory properties. Osteocytes perform bone remodeling based on the strains of the skeletal system, however the process of sensing and reacting to mechanical pressures remains illusive. The remodeling phenomenon occurs in all vertebrates, and there will be multiple animals compared in the experiments (in vitro). This property of osteocytes could improve understanding of osteoporosis, bone loss due to mechanical unloading (as observed in astronauts losing bone mass, or an individual that is suddenly confined to a wheel chair). Furthermore, this research could improve understanding of the bone remodeling that every human experiences as they age, and their bones become more brittle and sensitive (especially in women). Congratulations, Adam!
Emily Gibson, assistant professor of bioengineering, and colleagues with the CU School of Medicine and CU Boulder have created a miniature, fiber-optic microscope that can look deep inside a living brain. Their work was featured in the Denver Post on May 12. The research was made possible by a $1M grant from the National Science Foundation and will also be featured on the NSF website.
Read the Denver Post story here.
A team of electrical engineering students won first place at the Cornell Cup competition last weekend in Cape Canaveral, Florida.
Their project, Stratus, enables aerial and ground robotic systems to generate 3D models of local areas such as buildings as well as performed enhanced obstacle-aware navigation.
Their project will be on display at the Spring Senior Design Competition on May 15. There is a lot to show and build upon for both research and education.
Congratulations to the team, Skyler Saleh, Bruno Mary, Bruno Duarte, and Xin Li, and to their faculty advisor, Dan Connors. This is the third year the college has participated in this event.
Christopher Yakacki, assistant professor, has been named the 2015 campus winner for the Faculty Excellence in Research and Creative Activities award. He will be honored at a ceremony on September 18. The awards are special not just because they recognize outstanding performance in our core areas as a university, but also because they are ultimately recognition of this exemplary work by faculty peers. Recipients are chosen by selection committees comprising previous award winners. Congratulations, Chris! Read the entire announcement from Provost Nairn.
On Friday, April 17, more than 200 students from CU Denver and CU Anschutz participated in the 18th annual Research and Creative Activities Symposium. Ten schools and colleges were represented, and two participants from the College of Engineering and Applied Science walked away with awards.
Ashanthi Maxworth, graduate student in electrical engineering, received the Outstanding Graduate Scholarly Activity in Engineering and Applied Science award for her poster presentation, “Whistler Wave Propagation in the Earth’s Ionosphere and Magnetosphere.” Maxworth’s faculty sponsor is Mark Golkowski, assistant professor of electrical engineering.
CU Denver Motorsports, a team of mechanical engineering students, received the Outstanding Undergraduate Scholarly Activity in Engineering and Applied Science award for their senior design project, a formula one race car designed to compete in a collegiate competition this summer. Team members include Alex Fenstermacher, Chris Allen, Michael Baker, Zack Landgren, Byron Pindell, Matt Bunsness, Mark Haden, Austin Voss, Drake Soule, David Richards, Orlando Paredes, Arthur Boo, Tabitha Martinez, and Curtis Sharpsteen; their faculty sponsor is Ron Rorrer, associate professor of mechanical engineering.
Congratulations to all of you!
Read the event recap from University Communications.
Bill McIntyre, engineering and applied science PhD candidate in civil engineering, successfully defended his dissertation, titled “Alluvial Storage and Recovery in the South Platte River Basin in Colorado-A Design Approach,” on April 8, and is set to be the first graduate of the college’s interdisciplinary EAS PhD program. His graduate committee members include Associate Professor David Mays, Professor Emeritus Lynn Johnson, Assistant Professor Indrani Pal, Dick Wolf, Paul Flack, and Professor Kevin Rens, who is also his major professor, advisor and mentor.
McIntyre will be hooded at commencement on May 16.