Daewon Park, assistant professor of bioengineering, received American Heart Association Grant-in-Aid with his research titled “Engineered biomimetic injectable system towards cardiac repair”.
Myocardial infarction (MI) is a leading ischemic cardiovascular disease. Over recent decades, the number of medical treatment methodologies for patients with MI has steadily increased, with new treatments being developed every few years. However, even with this concerted attention from the medical and research communities, a significant percentage of MI patients have suffered a recurrent attack, despite receiving proper medical treatment. There is a clear unmet need for MI treatment that prevents recurrent attacks.
With this grant, Dr. Park will develop an alternative treatment strategy, using an injectable biomaterial with the capacity for localized co-delivery of therapeutic agents, to target key endogenous processes of the post-MI healing process: the anti-inflammatory reaction and the formation of new blood vessels.
This injectable biomaterial system addresses MI in a one-time treatment platform, removing the critical barrier of patient compliance thereby promoting therapeutic success.