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Park’s research selected for cover of Biomacromolecules

bomaf6_v017i005_CoverBioengineering assistant professor Daewon Park’s research “Biomimetic Polymers for Cardiac Tissue Engineering” was selected as the cover for the May 2016 issue of Biomacromolecules. About the cover: an injectable biomimetic reverse thermogel (RTG) was specifically engineered to support long-term cardiomyocyte (CM) survival. This RTG biopolymer provided a solution-based delivery vehicle of CMs, which transitioned to a gel-based matrix shortly after reaching body temperature. For this investigation, the RTG was biomolecule-functionalized with poly-L-lysine or laminin. We found that the protein-functionalized RTG stimulated neonatal rat ventricular myocytes (NRVM) to spread and form heart-like functional syncytia.

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