Bioengineering assistant professor Daewon Park’s research “Biomimetic Polymers for Cardiac Tissue Engineering” was selected as the cover for the May 2016 issue of Biomacromolecules. About the cover: an injectable biomimetic reverse thermogel (RTG) was specifically engineered to support long-term cardiomyocyte (CM) survival. This RTG biopolymer provided a solution-based delivery vehicle of CMs, which transitioned to a gel-based matrix shortly after reaching body temperature. For this investigation, the RTG was biomolecule-functionalized with poly-L-lysine or laminin. We found that the protein-functionalized RTG stimulated neonatal rat ventricular myocytes (NRVM) to spread and form heart-like functional syncytia.
At the CU Denver College of Engineering, Design and Computing, we focus on providing our students with a comprehensive engineering education at the undergraduate, graduate and professional level. Faculty conduct research that spans our five disciplines of civil, electrical and mechanical engineering, bioengineering, and computer science and engineering. The college collaborates with industry from around the state; our laboratories and research opportunities give students the hands-on experience they need to excel in the professional world.